Learn the best ways to manage stress and negativity in your life. Department of Justice. Drug Enforcement Administration. List of Controlled Substances. Updated May National Library of Medicine. Updated July 21, Thomas S. American Addiction Centers. Updated June 4, Endo Pharmaceuticals Inc. Lautieri A. Pharmacokinetics in Older Adults. Merck Manual. Updated December Hepat Mon. Wakim JH. Alleviating Symptoms of Withdrawal from an Opioid. Pain Ther. Food and Drug Administration.
Updated February 7, Bunchorntavakul C, Reddy KR. Clin Liver Dis. Brande L. Percocet Overdose. Updated September 5, Opioid Overdose Prevention Toolkit. If you have trouble swallowing extended-release capsules Xtampza ER , you can carefully open the capsule and sprinkle the contents on soft foods such as applesauce, pudding, yogurt, ice cream, or jam, then consume the mixture immediately.
Dispose of the empty capsule shells right away by flushing them down a toilet. Do not store the mixture for future use. If you have a feeding tube, the extended-release capsule contents can be poured into the tube.
Ask your doctor how you should take the medication and follow these directions carefully. If you are taking the concentrated solution, your doctor may tell you to mix the medication in a small amount of juice or semisolid food such as pudding or applesauce. Follow these directions carefully. Swallow the mixture right away; do not store it for later use. Your doctor will likely start you on a low dose of oxycodone and may increase this dose over time if your pain is not controlled.
After you take oxycodone for a period of time, your body may become used to the medication. If this happens, your doctor may need to increase your dose to control your pain. Your doctor may decrease your dose if you experience side effects. Talk to your doctor about how you are feeling during your treatment with oxycodone. Do not stop taking oxycodone without talking to your doctor.
If you stop taking this medication suddenly, you may experience withdrawal symptoms such as restlessness, watery eyes, runny nose, sneezing, yawning, sweating, chills, muscle or joint aches or pains, weakness, irritability, anxiety, depression, difficulty falling asleep or staying asleep, cramps, nausea, vomiting, diarrhea, loss of appetite, fast heartbeat, and fast breathing. Your doctor will probably decrease your dose gradually.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. If you are taking oxycodone on a regular schedule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not take more than one dose of the extended-release tablets or capsules in 12 hours. Oxycodone may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture not in the bathroom. You must immediately dispose of any medication that is outdated or no longer needed through a medicine take-back program. If you do not have a take-back program nearby or one that you can access promptly, flush any medication that is outdated or no longer needed down the toilet so that others will not take it.
Talk to your pharmacist about the proper disposal of your medication. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach.
In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at While taking oxycodone, you should talk to your doctor about having a rescue medication called naloxone readily available e.
Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood. Your doctor may also prescribe you naloxone if you are living in a household where there are small children or someone who has abused street or prescription drugs. Fast-acting oxycodone capsules and liquid take 30 to 60 minutes to work, but these wear off after 4 to 6 hours.
Slow-acting oxycodone tablets can take 1 to 2 days to work fully, but the pain relief will last longer. An oxycodone injection into a vein gives the quickest pain relief and works almost straight away.
Depending on why you're taking oxycodone, you may only need to take it for a short time. For example, if you're in pain after an injury or operation, you may only need to take oxycodone for a few days or weeks at most.
You may need to take it for longer if you have a long-term condition such as cancer. It is possible to become addicted to oxycodone. If you need to take if for a long time your body can become tolerant to it.
That means you need higher doses to control your pain over time. For this reason, the dose you take will be reviewed to make sure you are only taking the amount you need to control your pain. If you're addicted to oxycodone, you may find it difficult to stop taking it or feel you need to take it more often than necessary.
If you stop taking it suddenly you may suffer from withdrawal symptoms. These include:. Talk to a doctor if you're worried about addiction or if you want to know more about how to prevent withdrawal symptoms. For some people with conditions who need long-term pain relief, it may be necessary to take oxycodone for a long time.
If you need to take it for a long time, your body can become tolerant to it. Some people can become more sensitive to pain hyperalgesia.
If this happens, your doctor will reduce your dose gradually to help these symptoms. For this reason, your dose will be reviewed to make sure you are only taking the amount you need to control your pain. Your treatment plan may include details of how and when you will stop taking oxycodone. If you are having treatment for cancer pain or other severe pain, your pain control will be carefully monitored. Speak to your doctor if you are worried about tolerance, hyperalgesia or becoming addicted. If you need to take oxycodone for a long time, your body can get used to it.
This is not usually a problem, but if you stop taking it suddenly you could get withdrawal symptoms such as:. If you want to stop taking oxycodone, talk to a doctor first. Your dose can be reduced gradually so you do not get these symptoms. Oxycodone acts on different pain signals in the brain to some other opiates.
This does not mean it's better for certain conditions. The pain relief and side effects which you can get from oxycodone will be different for individual people. A doctor may prescribe oxycodone if you have had side effects from other opiates. It's best to stop drinking alcohol during the first few days of treatment, or if a doctor increases your dose, until you see how oxycodone affects you.
Drinking alcohol while you're taking oxycodone may make you feel more sleepy or increase the risk of serious side effects. Grapefruit juice can increase the amount of oxycodone in your body so it's a good idea to avoid it while you're taking oxycodone.
Oxycodone is not generally affected by any other food or drink except alcohol. Oxycodone does not affect any type of contraception including the combined pill or emergency contraception. There's no firm evidence to suggest that taking oxycodone will reduce fertility in women or men. However, speak to a pharmacist or doctor if you're trying to get pregnant. They may want to review your treatment. Do not drive a car, ride a bike or operate machinery if oxycodone gives you blurred vision, makes you feel dizzy, sleepy, clumsy or unable to concentrate or make decisions.
This may be more likely when you first start taking oxycodone but could happen at any time — for example when starting another medicine or if a doctor increases your dose. It's an offence to drive a car if your ability to drive safely is affected. It's your responsibility to decide if it's safe to drive.
If you're in any doubt, do not drive. It may be best not to drink alcohol while taking oxycodone as you're more likely to get side effects like feeling sleepy. Even if your ability to drive is not affected, police have the right to request a saliva sample to check how much morphine is in your body.
UK has more information about the law on drugs and driving. Talk to a doctor or pharmacist if you're unsure whether it's safe for you to drive while taking oxycodone. The amount of oxycodone needed for analgesia pain relief varies widely between people. Usually, a doctor will start you on a low dose and then increase the dose slowly until your pain is well controlled. People who have taken an opioid medication before may need to take a higher dose in order to experience pain relief.
Oxycodone is taken by mouth oral and should be taken with food. You should start feeling the effects of oxycodone in just 20 to 30 minutes. Oxycodone reaches peak concentrations in the bloodstream in roughly one to two hours following ingestion. Extended- and controlled-release formulations can take three to four hours to reach peak concentration in the bloodstream. Over time, you may build up a tolerance to oxycodone.
This means it may take longer to feel the pain relief or the relief may not feel as strong. When this happens, your doctor may want to increase your dose or switch you to a different type of pain medication. One way to find out how long a drug will last in your body is to measure its half-life. The half-life is the time it takes for half of the drug to be eliminated from the body. Immediate-release formulations of oxycodone have average half-life of 3.
In other words, it takes 3. It takes several half-lives to fully eliminate a drug. Since everyone metabolizes medications differently, the half-life will vary from person to person. For most people, oxycodone will fully clear the blood within 24 hours, but it can still be detected in the saliva, urine, or hair for longer than that. Controlled or extended-release formulations last longer, so they are usually taken every 12 hours. A number of factors can influence the time it takes for oxycodone to clear the body.
0コメント