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New-York: E. Dutton; Parkes Weber F. Cutaneous pigmentation as an incomplete form of Recklinhausen's disease, with remarks on the classification of incomplete and anomalous forms of Recklinhausen's disease.
Rai G, Coni N. A case report of neurofibromatosis. J Am Geriatr Soc. Floyd A, Percy-Lancaster R. The elephant woman. Hostamisligil G. Proteus syndrome and neurofibromatosis. Seward G. Morse RP. Neurofibromatosis type 1. Joseph Merrick the grotesquely…. What the Elephant Man really had. Newsweek; When is a single gene… Gene found for neurofibromatosis.
Science News. Friend T. Breakthrough in Elephant Man's disease. USA Today; Cause identified for disfiguring genetic disease. Rosenfeld A. Inside the Elephant Man. Discover; Williamson D. Mega-win, big pain; For some, dream can seem a nightmare. Engel J. Elephant Man Disease Not Neurofibromatosis. The New York Times; Without treatment, the condition will worsen over time. Treatment may include surgery and physical therapy.
Your child will also be monitored for blood clots. The condition can affect quality of life, but people with Proteus syndrome can age normally with medical intervention and monitoring.
Damage to blood vessels can cause bruising and blood clots, but the two conditions have many differences. Learn more about them. Babies develop and reach milestones at different ages. Does not walking by 14 months indicate a problem? Blood clotting is a normal function that occurs when you have an injury. Find out what happens if clot doesn't dissolve or forms in a blood vessel. Here are 16 of the best sunscreens on the market in spray, lotion, and solid forms, and for different needs.
They're tried and true. Everyone can benefit from a good facial cleanser, and many products are specially formulated for dry, sensitive skin. Blue lips are most often caused when something is preventing you from getting enough oxygen into your body. Read on to discover some of the causes of…. Health Conditions Discover Plan Connect. Measure content performance. Develop and improve products. List of Partners vendors. When he was just two years old, Joseph Merrick's mother noticed that some areas of his skin began to change.
Some darkened, discolored skin growths were appearing, and they began to look bumpy and rough. Lumps began to grow under the boy's skin—on his neck, his chest, and the back of his head.
Mary Jane Merrick began to worry about her son, Joseph, and the other boys were starting to make fun of him.
As Joseph grew older, he began to look even more strange. The right side of his head began to grow, as did his right arm and hand. By the time he was 12 years old, Joseph's hand was so deformed it became useless. The growths on his skin were now large and repulsive for most people to look at.
Over the next years and with the passing of his mother, Joseph left home, tried working in a factory but was abused by the workers there, and finally ended up in a freak show. By now his face was distorted by the overgrown half of his head, and the flesh around his nose had grown, too, leading the show promoter to dub Joseph "The Elephant Man.
Most people know the rest of the story from the movie, The Elephant Man , starring John Hurt: how, at first, a doctor, then others including royalty, came to see the intelligent, sensitive man behind the grotesque deformities. People have been moved by the universal message of tolerance of the differences found in Joseph Merrick's story. Merrick's head was 36 inches in circumference, his right wrist 12 inches and one of his fingers 5 inches.
His skin was also covered in warty growths, the largest of which exuded an unpleasant smell, according to his surgeon Frederick Treves. Apart from Merrick's deformities and the lameness in his hip, Treves said that Merrick was in generally good health. Treves presented Merrick at a meeting of the Pathological Society of London but Merrick declined further exams and presentations because they made him feel "like an animal in a cattle market.
When Merrick gained fame for his distorted figure, his condition was not officially diagnosed - but later research pointed his disorder to Proteus syndrome. As his head and facial deformities continued to grow, Merrick could no longer travel and live on his own.
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